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TargetSolute carrier family 15 member 1
LigandBDBM50162073
Substrate/Competitorn/a
Meas. Tech.ChEMBL_836147 (CHEMBL2077583)
IC50 400000±n/a nM
Citation Han, Hde Vrueh, RLRhie, JKCovitz, KMSmith, PLLee, CPOh, DMSadée, WAmidon, GL 5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter. Pharm Res15:1154-9 (1998) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Solute carrier family 15 member 1
Name:Solute carrier family 15 member 1
Synonyms:Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1
Type:PROTEIN
Mol. Mass.:78818.07
Organism:Homo sapiens (Human)
Description:ChEMBL_1488839
Residue:708
Sequence:
MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50162073
n/a
NameBDBM50162073
Synonyms:(S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)ethyl 2-amino-3-methylbutanoate | (S)-2-Amino-3-methyl-butyric acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester | CHEMBL1349 | VALACYCLOVIR
TypeSmall organic molecule
Emp. Form.C13H20N6O4
Mol. Mass.324.3357
SMILESCC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: