| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hydroxycarboxylic acid receptor 1 |
|---|
| Ligand | BDBM50336491 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_850283 (CHEMBL2150703) |
|---|
| EC50 | 184000±n/a nM |
|---|
| Citation |  Dvorak, CA; Liu, C; Shelton, J; Kuei, C; Sutton, SW; Lovenberg, TW; Carruthers, NI Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects. ACS Med Chem Lett3:637-639 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Hydroxycarboxylic acid receptor 1 |
|---|
| Name: | Hydroxycarboxylic acid receptor 1 |
|---|
| Synonyms: | G-protein coupled receptor 104 | GPR104 | GPR81 | HCA1 | HCAR1 | HCAR1_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39313.04 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_850283 |
|---|
| Residue: | 346 |
|---|
| Sequence: | MYNGSCCRIEGDTISQVMPPLLIVAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVA
DFLLMICLPFRTDYYLRRRHWAFGDIPCRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHP
HHAVNTISTRVAAGIVCTLWALVILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIM
FQLEFFMPLGIILFCSFKIVWSLRRRQQLARQARMKKATRFIMVVAIVFITCYLPSVSAR
LYFLWTVPSSACDPSVHGALHITLSFTYMNSMLDPLVYYFSSPSFPKFYNKLKICSLKPK
QPGHSKTQRPEEMPISNLGRRSCISVANSFQSQSDGQWDPHIVEWH
|
|
|
|---|
| BDBM50336491 |
|---|
| n/a |
|---|
| Name | BDBM50336491 |
|---|
| Synonyms: | 3-Hydroxy-benzoic acid | 3-Hydroxybenzoate | 3-Hydroxybenzoate, II | 3-hydroxybenzoic acid | CHEMBL65369 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H6O3 |
|---|
| Mol. Mass. | 138.1207 |
|---|
| SMILES | OC(=O)c1cccc(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
