| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin F |
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| Ligand | BDBM50392209 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_852645 (CHEMBL2157194) |
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| Ki | >40000±n/a nM |
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| Citation |  Frizler, M; Schmitz, J; Schulz-Fincke, AC; Gütschow, M Selective nitrile inhibitors to modulate the proteolytic synergism of cathepsins S and F. J Med Chem55:5982-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin F |
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| Name: | Cathepsin F |
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| Synonyms: | CATF_HUMAN | CATSF | CTSF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53373.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_852650 |
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| Residue: | 484 |
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| Sequence: | MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRA
VLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLL
RKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLP
VKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLT
EEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSV
TGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQ
GHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPL
RPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASS
AVVD
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| BDBM50392209 |
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| n/a |
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| Name | BDBM50392209 |
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| Synonyms: | CHEMBL2153172 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N3O4S |
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| Mol. Mass. | 351.421 |
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| SMILES | CC(C)CS(=O)(=O)C[C@H](NC(=O)c1ccccc1)C(=O)NCC#N |r| |
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| Structure | 
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