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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50392574 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_854395 (CHEMBL2154766) | ||
| Ki | 89.1±n/a nM | ||
| Citation |  Pasquini, S; De Rosa, M; Ligresti, A; Mugnaini, C; Brizzi, A; Caradonna, NP; Cascio, MG; Bolognini, D; Pertwee, RG; Di Marzo, V; Corelli, F Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors. Eur J Med Chem58:30-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
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| BDBM50392574 | |||
| n/a | |||
| Name | BDBM50392574 | ||
| Synonyms: | CHEMBL2152825 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H33N3O2S | ||
| Mol. Mass. | 475.646 | ||
| SMILES | CCCCCn1cc(C(=O)NC2CN3CCC2CC3)c(=O)c2ccc(Sc3ccccc3)cc12 |(41.89,-47.58,;40.56,-48.35,;39.22,-47.58,;37.89,-48.36,;36.56,-47.59,;36.55,-46.05,;37.9,-45.27,;37.89,-43.72,;39.22,-42.94,;39.22,-41.4,;40.56,-43.71,;41.89,-42.93,;41.7,-41.55,;43.16,-40.91,;44.51,-41.51,;44.79,-42.91,;43.42,-42.28,;43.68,-40.38,;43.23,-39.27,;36.54,-42.94,;36.53,-41.4,;35.2,-43.73,;33.87,-42.96,;32.54,-43.73,;32.54,-45.28,;31.2,-46.05,;29.87,-45.28,;29.88,-43.74,;28.55,-42.97,;27.21,-43.74,;27.22,-45.28,;28.55,-46.05,;33.87,-46.05,;35.21,-45.28,)| | ||
| Structure | 
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