| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Plasminogen |
|---|
| Ligand | BDBM50392589 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_854019 (CHEMBL2155316) |
|---|
| Ki | >20000±n/a nM |
|---|
| Citation |  Pandya, V; Jain, M; Chakrabarti, G; Soni, H; Parmar, B; Chaugule, B; Patel, J; Jarag, T; Joshi, J; Joshi, N; Rath, A; Unadkat, V; Sharma, B; Ajani, H; Kumar, J; Sairam, KV; Patel, H; Patel, P Synthesis and structure-activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: application of weakly basic sulfoximine group as novel S4 binding element. Eur J Med Chem58:136-52 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Plasminogen |
|---|
| Name: | Plasminogen |
|---|
| Synonyms: | Activation peptide | Angiostatin | PLG | PLMN_HUMAN | Plasmin | Plasmin heavy chain A | Plasmin heavy chain A, short form | Plasmin light chain B |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 90579.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 810 |
|---|
| Sequence: | MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE
LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS
AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE
QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG
LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED
CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG
PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT
RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE
PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ
LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW
GLGCARPNKPGVYVRVSRFVTWIEGVMRNN
|
|
|
|---|
| BDBM50392589 |
|---|
| n/a |
|---|
| Name | BDBM50392589 |
|---|
| Synonyms: | CHEMBL2153377 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H21Cl2N5O4S |
|---|
| Mol. Mass. | 546.426 |
|---|
| SMILES | CCN=CC(=O)N=S(C)(=O)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 |w:3.3| |
|---|
| Structure | 
|
|---|
Search and Browse
