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TargetProstaglandin E synthase
LigandBDBM50393041
Substrate/Competitorn/a
Meas. Tech.ChEMBL_853594 (CHEMBL2154049)
IC50 792±n/a nM
Citation Abdel-Magid, AF Prostaglandin e2 synthase-1 inhibitors as potential treatment for osteoarthritis: patent highlight. ACS Med Chem Lett3:703-704 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E synthase
Name:Prostaglandin E synthase
Synonyms:MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1)
Type:Protein
Mol. Mass.:17112.22
Organism:Homo sapiens (Human)
Description:n/a
Residue:152
Sequence:
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
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BDBM50393041
n/a
NameBDBM50393041
Synonyms:CHEMBL2152711
TypeSmall organic molecule
Emp. Form.C15H17ClN4O2
Mol. Mass.320.774
SMILESCC(C)C(=O)NCc1ccc(Cl)c(c1)C(=O)Nc1ncc[nH]1
Structure
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