| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix metalloproteinase-9 |
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| Ligand | BDBM50215926 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_853826 (CHEMBL2154852) |
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| IC50 | 2210±n/a nM |
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| Citation |  Shengule, SR; Loa-Kum-Cheung, WL; Parish, CR; Blairvacq, M; Meijer, L; Nakao, Y; Karuso, P A one-pot synthesis and biological activity of ageladine A and analogues. J Med Chem54:2492-503 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix metalloproteinase-9 |
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| Name: | Matrix metalloproteinase-9 |
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| Synonyms: | 67 kDa matrix metalloproteinase-9 | 82 kDa matrix metalloproteinase-9 | 92 kDa gelatinase | 92 kDa type IV collagenase | CLG4B | GELB | Gelatinase B | MMP-9 | MMP9 | MMP9_HUMAN | Matrix metalloproteinase 9 (MMP-9) | Matrix metalloproteinase-9 (MMP-9) | Matrix metalloproteinase-9 (MMP9) |
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| Type: | Enzyme |
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| Mol. Mass.: | 78452.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14780 |
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| Residue: | 707 |
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| Sequence: | MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM
RGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHN
ITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP
FDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRS
YSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYS
ACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYST
CTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY
PMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSER
PTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYW
RFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRR
LDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLD
THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED
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| BDBM50215926 |
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| n/a |
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| Name | BDBM50215926 |
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| Synonyms: | 4-(4,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine | Ageladine A | CHEMBL230806 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H7Br2N5 |
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| Mol. Mass. | 357.004 |
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| SMILES | Nc1nc2c(nccc2[nH]1)-c1cc(Br)c(Br)[nH]1 |
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| Structure | 
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