| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase ULK1 |
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| Ligand | BDBM50393109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_853870 (CHEMBL2154990) |
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| Kd | 24000±n/a nM |
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| Citation |  Shengule, SR; Loa-Kum-Cheung, WL; Parish, CR; Blairvacq, M; Meijer, L; Nakao, Y; Karuso, P A one-pot synthesis and biological activity of ageladine A and analogues. J Med Chem54:2492-503 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase ULK1 |
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| Name: | Serine/threonine-protein kinase ULK1 |
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| Synonyms: | ATG1 | Autophagy-related protein 1 homolog | KIAA0722 | ULK1 | ULK1_HUMAN | Unc-51-like kinase 1 | hATG1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 112661.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1510275 |
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| Residue: | 1050 |
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| Sequence: | MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL
GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQ
QIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAAT
LCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLV
PTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGS
GSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMV
PAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGP
FSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPLGFARASPSP
PAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSA
PEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCR
NLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRT
LPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESL
QEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTG
SASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEH
TEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQL
VLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRF
FLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHM
LSDQADIENVTKCKLCIERRLSALLTGICA
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| BDBM50393109 |
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| n/a |
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| Name | BDBM50393109 |
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| Synonyms: | CHEMBL2153264 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H9N5 |
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| Mol. Mass. | 211.2227 |
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| SMILES | Nc1nc2c(nccc2[nH]1)-c1ccccn1 |
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| Structure | 
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