| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
|---|
| Ligand | BDBM50215926 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_853880 (CHEMBL2155000) |
|---|
| IC50 | 10000±n/a nM |
|---|
| Citation |  Shengule, SR; Loa-Kum-Cheung, WL; Parish, CR; Blairvacq, M; Meijer, L; Nakao, Y; Karuso, P A one-pot synthesis and biological activity of ageladine A and analogues. J Med Chem54:2492-503 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase pim-1 |
|---|
| Name: | Serine/threonine-protein kinase pim-1 |
|---|
| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35681.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11309 |
|---|
| Residue: | 313 |
|---|
| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
|
|
|
|---|
| BDBM50215926 |
|---|
| n/a |
|---|
| Name | BDBM50215926 |
|---|
| Synonyms: | 4-(4,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine | Ageladine A | CHEMBL230806 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H7Br2N5 |
|---|
| Mol. Mass. | 357.004 |
|---|
| SMILES | Nc1nc2c(nccc2[nH]1)-c1cc(Br)c(Br)[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
