| Reaction Details |
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 | Report a problem with these data |
| Target | Succinate receptor 1 |
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| Ligand | BDBM50393120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_852820 (CHEMBL2156127) |
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| IC50 | 41±n/a nM |
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| Citation |  Bhuniya, D; Umrani, D; Dave, B; Salunke, D; Kukreja, G; Gundu, J; Naykodi, M; Shaikh, NS; Shitole, P; Kurhade, S; De, S; Majumdar, S; Reddy, SB; Tambe, S; Shejul, Y; Chugh, A; Palle, VP; Mookhtiar, KA; Cully, D; Vacca, J; Chakravarty, PK; Nargund, RP; Wright, SD; Graziano, MP; Singh, SB; Roy, S; Cai, TQ Discovery of a potent and selective small molecule hGPR91 antagonist. Bioorg Med Chem Lett21:3596-602 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Succinate receptor 1 |
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| Name: | Succinate receptor 1 |
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| Synonyms: | G-protein coupled receptor 91 | GPR91 | P2Y purinoceptor 1-like | SUCNR1 | SUCR1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38709.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_852820 |
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| Residue: | 334 |
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| Sequence: | MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNI
YLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDR
YLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGD
PNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVI
FSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGD
HFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK
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| BDBM50393120 |
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| n/a |
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| Name | BDBM50393120 |
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| Synonyms: | CHEMBL2153443 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21F4N3O |
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| Mol. Mass. | 467.4581 |
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| SMILES | Fc1cc(ccc1CNC(=O)CCCc1ccc2cccnc2n1)-c1cccc(c1)C(F)(F)F |
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| Structure | 
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