| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50393177 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_852592 (CHEMBL2156703) |
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| Ki | 2490±n/a nM |
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| Citation |  Drabczynska, A; Yuzlenko, O; Köse, M; Paskaleva, M; Schiedel, AC; Karolak-Wojciechowska, J; Handzlik, J; Karcz, T; Kuder, K; Müller, CE; Kiec-Kononowicz, K Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones. Eur J Med Chem46:3590-607 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50393177 |
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| n/a |
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| Name | BDBM50393177 |
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| Synonyms: | CHEMBL2153618 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25N5O2 |
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| Mol. Mass. | 331.4127 |
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| SMILES | Cn1c2nc3N(CC4CCCCC4)CCCn3c2c(=O)n(C)c1=O |
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| Structure | 
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