| Reaction Details |
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 | Report a problem with these data |
| Target | Quinolone resistance protein NorA |
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| Ligand | BDBM50393707 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_856643 (CHEMBL2162180) |
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| IC50 | 9000±n/a nM |
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| Citation |  Holler, JG; Slotved, HC; Mølgaard, P; Olsen, CE; Christensen, SB Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles. Bioorg Med Chem20:4514-21 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Quinolone resistance protein NorA |
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| Name: | Quinolone resistance protein NorA |
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| Synonyms: | NORA_STAAU | norA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42273.03 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_961221 |
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| Residue: | 388 |
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| Sequence: | MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLVAAFALSQMIISPFGGT
LADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIADIS
PSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFYFAGALGILAFIMSIVLIHDP
KKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAFETLYSLYTADKVNYSPKDI
SIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLVFANGYWSIMLISF
VVFIGFDMIRPAITNYFSNIAGERQGFAGGLNSTFTSMGNFIGPLIAGALFDVHIEAPIY
MAIGVSLAGVVIVLIEKQHRAKLKEQNM
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| BDBM50393707 |
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| n/a |
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| Name | BDBM50393707 |
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| Synonyms: | CHEMBL2158998 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25NO3 |
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| Mol. Mass. | 387.4709 |
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| SMILES | CN(C)CCOc1ccc(cc1)C(=O)\C=C\c1ccc(Oc2ccccc2)cc1 |
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| Structure | 
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