| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-butyrobetaine dioxygenase |
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| Ligand | BDBM50395079 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859436 (CHEMBL2167514) |
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| IC50 | >100000±n/a nM |
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| Citation |  Rose, NR; Woon, EC; Tumber, A; Walport, LJ; Chowdhury, R; Li, XS; King, ON; Lejeune, C; Ng, SS; Krojer, T; Chan, MC; Rydzik, AM; Hopkinson, RJ; Che, KH; Daniel, M; Strain-Damerell, C; Gileadi, C; Kochan, G; Leung, IK; Dunford, J; Yeoh, KK; Ratcliffe, PJ; Burgess-Brown, N; von Delft, F; Muller, S; Marsden, B; Brennan, PE; McDonough, MA; Oppermann, U; Klose, RJ; Schofield, CJ; Kawamura, A Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J Med Chem55:6639-43 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-butyrobetaine dioxygenase |
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| Name: | Gamma-butyrobetaine dioxygenase |
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| Synonyms: | BBH | BBOX | BBOX1 | BODG_HUMAN | Gamma-BBH | Gamma-butyrobetaine hydroxylase | Gamma-butyrobetaine,2-oxoglutarate dioxygenase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44715.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1434107 |
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| Residue: | 387 |
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| Sequence: | MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV
NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL
QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT
WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK
LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF
DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR
HLEGAYADWDVVMSRLRILRQRVENGN
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| BDBM50395079 |
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| n/a |
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| Name | BDBM50395079 |
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| Synonyms: | CHEMBL2164244 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H15N2O3 |
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| Mol. Mass. | 175.2051 |
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| SMILES | C[N+](C)(C)NC(=O)CCC(O)=O |
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| Structure | 
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