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TargetGamma-butyrobetaine dioxygenase
LigandBDBM50395080
Substrate/Competitorn/a
Meas. Tech.ChEMBL_859436
IC50>100000±n/a nM
Citation Rose NRWoon ECTumber AWalport LJChowdhury RLi XSKing ONLejeune CNg SSKrojer TChan MCRydzik AMHopkinson RJChe KHDaniel MStrain-Damerell CGileadi CKochan GLeung IKDunford JYeoh KKRatcliffe PJBurgess-Brown Nvon Delft FMuller SMarsden BBrennan PEMcDonough MAOppermann UKlose RJSchofield CJKawamura A Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J Med Chem 55:6639-43 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gamma-butyrobetaine dioxygenase
Name:Gamma-butyrobetaine dioxygenase
Synonyms:BBH | BBOX | BBOX1 | Gamma-BBH | Gamma-butyrobetaine hydroxylase | Gamma-butyrobetaine,2-oxoglutarate dioxygenase
Type:PROTEIN
Mol. Mass.:44715.93
Organism:Homo sapiens (Human)
Description:ChEMBL_1434107
Residue:387
Sequence:
MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV
NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL
QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT
WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK
LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF
DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR
HLEGAYADWDVVMSRLRILRQRVENGN
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  Blast E-value cutoff:
BDBM50395080
n/a
NameBDBM50395080
Synonyms:CHEMBL2164249
TypeSmall organic molecule
Emp. Form.C6H11NO4
Mol. Mass.161.1558
SMILESCN(C)OC(=O)CCC(O)=O
Structure
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