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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histone Lysine Demethylase | ||
| Ligand | BDBM50395080 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_859441 | ||
| IC50 | >100000±n/a nM | ||
| Citation |  Rose NR; Woon EC; Tumber A; Walport LJ; Chowdhury R; Li XS; King ON; Lejeune C; Ng SS; Krojer T; Chan MC; Rydzik AM; Hopkinson RJ; Che KH; Daniel M; Strain-Damerell C; Gileadi C; Kochan G; Leung IK; Dunford J; Yeoh KK; Ratcliffe PJ; Burgess-Brown N; von Delft F; Muller S; Marsden B; Brennan PE; McDonough MA; Oppermann U; Klose RJ; Schofield CJ; Kawamura A Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J Med Chem 55:6639-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histone Lysine Demethylase | |||
| Name: | Histone Lysine Demethylase | ||
| Synonyms: | 2-OG-Dependent Histone Demethylase JMJD2E | Jumonji domain-containing protein 2E (JMJD2E) | KDM4D-like protein | Lysine-specific demethylase 4D-like | Lysine-specific demethylase 4E | Lysine-specific demethylase 4E (KDM4E) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56815.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | B2RXH2 | ||
| Residue: | 506 | ||
| Sequence: |
| ||
| BDBM50395080 | |||
| n/a | |||
| Name | BDBM50395080 | ||
| Synonyms: | CHEMBL2164249 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C6H11NO4 | ||
| Mol. Mass. | 161.1558 | ||
| SMILES | CN(C)OC(=O)CCC(O)=O | ||
| Structure | 
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