| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50395107 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859459 (CHEMBL2167537) |
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| Ki | 2.75±n/a nM |
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| Citation |  Majumdar, S; Subrath, J; Le Rouzic, V; Polikar, L; Burgman, M; Nagakura, K; Ocampo, J; Haselton, N; Pasternak, AR; Grinnell, S; Pan, YX; Pasternak, GW Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associatedµ opioid receptor (MOR-1) splice variants. J Med Chem55:6352-62 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | KOR-1 | MSL-1 | OPIATE Kappa | OPRK_MOUSE | Oprk1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42656.78 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P33534 |
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| Residue: | 380 |
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| Sequence: | MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
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| BDBM50395107 |
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| n/a |
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| Name | BDBM50395107 |
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| Synonyms: | CHEMBL2163546 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N2O5 |
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| Mol. Mass. | 448.5109 |
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| SMILES | Oc1cccc(c1)C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45 |r| |
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| Structure | 
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