| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50395138 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859793 (CHEMBL2169621) |
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| Ki | 10.2±n/a nM |
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| Citation |  Baraldi, PG; Saponaro, G; Moorman, AR; Romagnoli, R; Preti, D; Baraldi, S; Ruggiero, E; Varani, K; Targa, M; Vincenzi, F; Borea, PA; Aghazadeh Tabrizi, M 7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as selective CB(2) cannabinoid receptor ligands: structural investigations around a novel class of full agonists. J Med Chem55:6608-23 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39366.68 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9QZN9 |
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| Residue: | 360 |
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| Sequence: | MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
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| BDBM50395138 |
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| n/a |
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| Name | BDBM50395138 |
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| Synonyms: | CHEMBL2163928 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N2O3 |
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| Mol. Mass. | 420.5439 |
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| SMILES | CC(C)C[C@@H]1COc2cccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O |r,THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| |
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| Structure | 
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