| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50395207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859983 (CHEMBL2167566) |
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| Ki | 1.21±n/a nM |
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| Citation |  Mangin, F; Dilly, S; Joly, B; Scuvée-Moreau, J; Evans, J; Setola, V; Roth, BL; Liégeois, JF Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors. Bioorg Med Chem Lett22:4550-4 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50395207 |
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| n/a |
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| Name | BDBM50395207 |
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| Synonyms: | CHEMBL2164350 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H32N4O |
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| Mol. Mass. | 392.5371 |
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| SMILES | O=C(C1CCCCC1)N(CCN1CCN(CC1)c1ccccc1)c1ccccn1 |
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| Structure | 
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