| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A (5-HT1A) |
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| Ligand | BDBM50395578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859668 |
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| Ki | 0.6±n/a nM |
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| Citation |  Chen X; Sassano MF; Zheng L; Setola V; Chen M; Bai X; Frye SV; Wetsel WC; Roth BL; Jin J Structure-functional selectivity relationship studies ofß-arrestin-biased dopamine D2 receptor agonists. J Med Chem 55:7141-53 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A (5-HT1A) |
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| Name: | 5-hydroxytryptamine receptor 1A (5-HT1A) |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50395578 |
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| n/a |
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| Name | BDBM50395578 |
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| Synonyms: | CHEMBL2165137 | UNC10099993 | US9156822, 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24Cl2N2OS |
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| Mol. Mass. | 435.41 |
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| SMILES | Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl |
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| Structure | 
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