| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase A1 |
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| Ligand | BDBM50395590 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859685 (CHEMBL2169120) |
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| Ki | 71000±n/a nM |
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| Citation |  Koutsoumpli, GE; Dimaki, VD; Thireou, TN; Eliopoulos, EE; Labrou, NE; Varvounis, GI; Clonis, YD Synthesis and study of 2-(pyrrolesulfonylmethyl)-N-arylimines: a new class of inhibitors for human glutathione transferase A1-1. J Med Chem55:6802-13 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase A1 |
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| Name: | Glutathione S-transferase A1 |
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| Synonyms: | GST class-alpha member 1 | GST-epsilon | GSTA1 | GSTA1-1 | GSTA1_HUMAN | GTH1 | Glutathione S-transferase (GST) | HA subunit 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 25636.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Glutathione-S-Transferase (GST, N-terminally) |
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| Residue: | 222 |
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| Sequence: | MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
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| BDBM50395590 |
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| n/a |
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| Name | BDBM50395590 |
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| Synonyms: | CHEMBL2165141 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N3O4S |
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| Mol. Mass. | 383.421 |
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| SMILES | Cn1cccc1S(=O)(=O)Cc1ccccc1\N=C\c1ccc(cc1)[N+]([O-])=O |
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| Structure | 
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