Reaction Details |
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Target | Glutathione S-transferase A1 |
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Ligand | BDBM50395591 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_859685 (CHEMBL2169120) |
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Ki | 135000±n/a nM |
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Citation | Koutsoumpli, GE; Dimaki, VD; Thireou, TN; Eliopoulos, EE; Labrou, NE; Varvounis, GI; Clonis, YD Synthesis and study of 2-(pyrrolesulfonylmethyl)-N-arylimines: a new class of inhibitors for human glutathione transferase A1-1. J Med Chem55:6802-13 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Glutathione S-transferase A1 |
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Name: | Glutathione S-transferase A1 |
Synonyms: | GST class-alpha member 1 | GST-epsilon | GSTA1 | GSTA1-1 | GSTA1_HUMAN | GTH1 | Glutathione S-transferase (GST) | HA subunit 1 |
Type: | Enzyme |
Mol. Mass.: | 25636.31 |
Organism: | Homo sapiens (Human) |
Description: | Glutathione-S-Transferase (GST, N-terminally) |
Residue: | 222 |
Sequence: | MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
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BDBM50395591 |
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n/a |
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Name | BDBM50395591 |
Synonyms: | CHEMBL2165146 |
Type | Small organic molecule |
Emp. Form. | C12H12N2O4S |
Mol. Mass. | 280.3 |
SMILES | Cn1cccc1S(=O)(=O)Cc1ccccc1[N+]([O-])=O |
Structure |
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