| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SUV39H1 |
|---|
| Ligand | BDBM50134315 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_861232 (CHEMBL2173370) |
|---|
| IC50 | 260±n/a nM |
|---|
| Citation |  Decarlo, D; Hadden, MK Oncoepigenomics: making histone lysine methylation count. Eur J Med Chem56:179-194 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone-lysine N-methyltransferase SUV39H1 |
|---|
| Name: | Histone-lysine N-methyltransferase SUV39H1 |
|---|
| Synonyms: | H3-K9-HMTase 1 | Histone H3-K9 methyltransferase 1 | KMT1A | Lysine N-methyltransferase 1A | Position-effect variegation 3-9 homolog | SUV39H | SUV39H1 | SUV91_HUMAN | Su(var)3-9 homolog 1 | Suppressor of variegation 3-9 homolog 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47917.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1473655 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
|
|
|
|---|
| BDBM50134315 |
|---|
| n/a |
|---|
| Name | BDBM50134315 |
|---|
| Synonyms: | 7-hydroxy-11-hydroxymethyl-12-methyl-14,15-dithia-9,12-diazatetracyclo[9.2.2.01,9.03,8]pentadeca-3,5-diene-10,13-dione | CHEMBL331627 | GLIOTOXIN |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14N2O4S2 |
|---|
| Mol. Mass. | 326.391 |
|---|
| SMILES | CN1C(=O)[C@]23CC4=CC=C[C@H](O)[C@H]4N2C(=O)[C@@]1(CO)SS3 |r,c:8,t:6,THB:12:13:1.2:19.20,15:14:1.2:19.20| |
|---|
| Structure | 
|
|---|
Search and Browse
