| Reaction Details |
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 | Report a problem with these data |
| Target | Prostate-specific antigen |
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| Ligand | BDBM50298759 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_862795 (CHEMBL2172815) |
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| Ki | 65±n/a nM |
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| Citation |  Caliendo, G; Santagada, V; Perissutti, E; Severino, B; Fiorino, F; Frecentese, F; Juliano, L Kallikrein protease activated receptor (PAR) axis: an attractive target for drug development. J Med Chem55:6669-86 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostate-specific antigen |
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| Name: | Prostate-specific antigen |
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| Synonyms: | APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28747.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_959198 |
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| Residue: | 261 |
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| Sequence: | MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
SLYTKVVHYRKWIKDTIVANP
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| BDBM50298759 |
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| n/a |
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| Name | BDBM50298759 |
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| Synonyms: | (5S,8S,11S,14S,17R)-11-(4-aminobutyl)-5,8-bis(hydroxymethyl)-14-isobutyl-19-methyl-3,6,9,12,15-pentaoxo-1-phenyl-2-oxa-4,7,10,13,16-pentaazaicosan-17-ylboronic acid | CHEMBL582947 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H53BN6O10 |
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| Mol. Mass. | 680.598 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1)B(O)O |r| |
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| Structure | 
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