| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-1 |
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| Ligand | BDBM50396164 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_862796 (CHEMBL2172816) |
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| Ki | 8±n/a nM |
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| Citation |  Caliendo, G; Santagada, V; Perissutti, E; Severino, B; Fiorino, F; Frecentese, F; Juliano, L Kallikrein protease activated receptor (PAR) axis: an attractive target for drug development. J Med Chem55:6669-86 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-1 |
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| Name: | Kallikrein-1 |
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| Synonyms: | KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein |
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| Type: | Enzyme |
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| Mol. Mass.: | 28874.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06870 |
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| Residue: | 262 |
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| Sequence: | MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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| BDBM50396164 |
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| n/a |
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| Name | BDBM50396164 |
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| Synonyms: | CHEMBL2171751 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H60N8O9 |
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| Mol. Mass. | 820.974 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(N)=O |r| |
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| Structure | 
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