| Reaction Details |
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 | Report a problem with these data |
| Target | 2-Hydroxyacid oxidase 2 |
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| Ligand | BDBM50396185 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_863186 (CHEMBL2175910) |
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| IC50 | 950±n/a nM |
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| Citation |  Barawkar, DA; Bandyopadhyay, A; Deshpande, A; Koul, S; Kandalkar, S; Patil, P; Khose, G; Vyas, S; Mone, M; Bhosale, S; Singh, U; De, S; Meru, A; Gundu, J; Chugh, A; Palle, VP; Mookhtiar, KA; Vacca, JP; Chakravarty, PK; Nargund, RP; Wright, SD; Roy, S; Graziano, MP; Cully, D; Cai, TQ; Singh, SB Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidase. Bioorg Med Chem Lett22:4341-7 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-Hydroxyacid oxidase 2 |
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| Name: | 2-Hydroxyacid oxidase 2 |
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| Synonyms: | (S)-2-hydroxy-acid oxidase, peroxisomal | Cell growth-inhibiting gene 16 protein | HAO2 | HAOX2 | HAOX2_HUMAN | Hydroxyacid oxidase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38843.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_863186 |
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| Residue: | 351 |
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| Sequence: | MSLVCLTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDT
RTTIQGEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAA
PEGLRWFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQLRRNLTLT
DLQSPKKGNAIPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDAELAVKHNVQG
IIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKALALGAKCIFLG
RPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLVQFSRL
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| BDBM50396185 |
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| n/a |
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| Name | BDBM50396185 |
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| Synonyms: | CHEMBL2172058 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13FN2O2 |
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| Mol. Mass. | 296.2957 |
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| SMILES | Cc1n[nH]c(C(O)=O)c1-c1cccc(c1)-c1ccc(F)cc1 |
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| Structure | 
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