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TargetProstaglandin E synthase
LigandBDBM50397228
Substrate/Competitorn/a
Meas. Tech.ChEMBL_864584
IC50 160±n/a nM
Citation Elkady MNieß RSchaible AMBauer JLuderer SAmbrosi GWerz OLaufer SA Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX. J Med Chem 55:8958-62 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E synthase
Name:Prostaglandin E synthase
Synonyms:Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E2 synthase-1 ( mPGES-1)
Type:Protein
Mol. Mass.:17112.22
Organism:Homo sapiens (Human)
Description:n/a
Residue:152
Sequence:
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
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BDBM50397228
n/a
NameBDBM50397228
Synonyms:CHEMBL2172775
TypeSmall organic molecule
Emp. Form.C25H17ClN2O2
Mol. Mass.412.868
SMILESOC(=O)Cc1cn(nc1-c1ccc(cc1)C#Cc1ccc(Cl)cc1)-c1ccccc1
Structure
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