| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division related protein kinase 2 |
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| Ligand | BDBM78336 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_862287 (CHEMBL2173143) |
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| IC50 | 11000±n/a nM |
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| Citation |  Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett22:6788-93 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division related protein kinase 2 |
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| Name: | Cell division related protein kinase 2 |
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| Synonyms: | CRK3 | Cdc2-related kinase | Cell division related protein kinase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35647.04 |
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| Organism: | Leishmania major |
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| Description: | ChEMBL_862288 |
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| Residue: | 311 |
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| Sequence: | MSSFGRVTARSGDAGTRDSLDRYNRLDVLGEGTYGVVYRAVDKITGQYVALKKVRLDRTE
EGIPQTALREVSILQEFDHPNIVNLLDVICSDGKLYLVFEYVEADLKKAIEKQEGGYSGM
DLKRLIYQLLDGLYFCHRHRIIHRDLKPANILLTSGNVLKLADFGLARAFQVPMHTYTHE
VVTLWYRAPEILLGEKHYTPAVDMWSVGCIFAELTRRKVLFRGDSEIGQLFEIFQVLGTP
TDTEGSWPGVSRLPDYRDVFPKWTAKRLGQVLPELHPDAIDLLSKMLKYDPRERISAKEA
LQHPWFSDLRW
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| BDBM78336 |
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| n/a |
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| Name | BDBM78336 |
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| Synonyms: | (6E)-6-[4-(3-pyridinylmethylamino)-1H-quinazolin-2-ylidene]-1-cyclohexa-2,4-dienone | (6E)-6-[4-(3-pyridylmethylamino)-1H-quinazolin-2-ylidene]cyclohexa-2,4-dien-1-one | (6E)-6-[4-(pyridin-3-ylmethylamino)-1H-quinazolin-2-ylidene]cyclohexa-2,4-dien-1-one | 2-{4-[(Pyridin-3-ylmethyl)-amino]-quinazolin-2-yl}-phenol | CHEMBL1328065 | MLS001043268 | SMR000415065 | cid_6097933 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N4O |
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| Mol. Mass. | 328.3672 |
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| SMILES | Oc1ccccc1-c1nc(NCc2cccnc2)c2ccccc2n1 |
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| Structure | 
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