| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium-dependent protein kinase 4 |
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| Ligand | BDBM50383381 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_862298 (CHEMBL2173154) |
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| IC50 | 4±n/a nM |
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| Citation |  Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett22:6788-93 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium-dependent protein kinase 4 |
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| Name: | Calcium-dependent protein kinase 4 |
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| Synonyms: | CDPK4 | CDPK4_PLAF7 | CPK4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60782.05 |
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| Organism: | Plasmodium falciparum (isolate 3D7) |
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| Description: | ChEMBL_862298 |
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| Residue: | 528 |
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| Sequence: | MGQEVSSVNNTKNEHHKTNKKSLKGGNERHEMKESSVGISKKIVENSFNNSKLRPGMFIQ
NSNVVFNEQYKGIKILGKGSFGEVILSRDKHTGHEYAIKVISKKHVKRKTDKESLLREVE
LLKMLDHINIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSG
ITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAP
DVLHGTYDEKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVEAGKYTFDLPQFKKISDK
AKDLIKKMLMYTSAVRISARDALEHEWIKMMTSKDNLNIDIPSLELSIANIRQFQSTQKL
AQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLD
NAAIEYEVDQILNSIDLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKIS
ANELAQLFGLSDVSSECWKTVLKEVDQNNDGEIDFKEFRDMLVKLCNY
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| BDBM50383381 |
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| n/a |
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| Name | BDBM50383381 |
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| Synonyms: | CHEMBL2030554 | CHEMBL2070050 | US10544104, Compound 29 | US11247972, Compound 29 | US9765037, Compound 29 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N6O |
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| Mol. Mass. | 402.4921 |
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| SMILES | CCOc1ccc2cc(ccc2c1)-c1nn(CC2CCNCC2)c2ncnc(N)c12 |
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| Structure | 
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