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TargetLysophosphatidic acid receptor 3
LigandBDBM50398108
Substrate/Competitorn/a
Meas. Tech.ChEMBL_873924 (CHEMBL2184760)
IC50>30000±n/a nM
Citation Qian, YHamilton, MSidduri, AGabriel, SRen, YPeng, RKondru, RNarayanan, ATruitt, THamid, RChen, YZhang, LFretland, AJSanchez, RAChang, KCLucas, MSchoenfeld, RCLaine, DFuentes, MEStevenson, CSBudd, DC Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts. J Med Chem55:7920-39 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lysophosphatidic acid receptor 3
Name:Lysophosphatidic acid receptor 3
Synonyms:EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:Enzyme
Mol. Mass.:40149.72
Organism:Homo sapiens (Human)
Description:Q9UBY5
Residue:353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
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  Blast E-value cutoff:
BDBM50398108
n/a
NameBDBM50398108
Synonyms:CHEMBL2182056
TypeSmall organic molecule
Emp. Form.C19H18ClN3O2
Mol. Mass.355.818
SMILESCC(OC(=O)Nc1c(cnn1C)-c1ccccc1)c1ccccc1Cl
Structure
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