| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-C chemokine receptor type 1 |
|---|
| Ligand | BDBM50099480 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_875652 (CHEMBL2184883) |
|---|
| IC50 | 450±n/a nM |
|---|
| Citation |  Pease, J; Horuk, R Chemokine receptor antagonists. J Med Chem55:9363-92 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-C chemokine receptor type 1 |
|---|
| Name: | C-C chemokine receptor type 1 |
|---|
| Synonyms: | C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41180.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P32246 |
|---|
| Residue: | 355 |
|---|
| Sequence: | METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLV
QYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTH
HTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRL
IFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVI
YAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
|
|
|
|---|
| BDBM50099480 |
|---|
| n/a |
|---|
| Name | BDBM50099480 |
|---|
| Synonyms: | 2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide | CHEMBL20532 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H21Cl2N3OS2 |
|---|
| Mol. Mass. | 466.447 |
|---|
| SMILES | Clc1ccc(CN2CCC(CC2)NC(=O)CSc2nc3ccccc3s2)cc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
