| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 1 |
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| Ligand | BDBM50203012 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_875624 (CHEMBL2184855) |
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| IC50 | 22±n/a nM |
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| Citation |  Pease, J; Horuk, R Chemokine receptor antagonists. J Med Chem55:9363-92 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 1 |
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| Name: | C-X-C chemokine receptor type 1 |
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| Synonyms: | C-X-C chemokine receptor type 1 (CXCR-1) | C-X-C chemokine receptor type 1 (CXCR1) | CMKAR1 | CXCR1 | CXCR1_HUMAN | IL8RA | Interleukin-8 receptor A | Interleukin-8 receptors, CXCR1/CXCR2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39803.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25024 |
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| Residue: | 350 |
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| Sequence: | MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLV
MLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVN
FYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHP
NNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRA
MRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCL
NPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
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| BDBM50203012 |
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| n/a |
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| Name | BDBM50203012 |
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| Synonyms: | 1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea | CHEMBL239767 | SB-225002 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10BrN3O4 |
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| Mol. Mass. | 352.14 |
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| SMILES | Oc1cc(ccc1NC(=O)Nc1ccccc1Br)[N+]([O-])=O |
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| Structure | 
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