Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Estrogen receptor | ||
Ligand | BDBM50398932 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_874806 (CHEMBL2188850) | ||
EC50 | 0.12±n/a nM | ||
Citation | Schäfer, A; Wellner, A; Strauss, M; Schäfer, A; Wolber, G; Gust, R Influence of chlorine or fluorine substitution on the estrogenic properties of 1-alkyl-2,3,5-tris(4-hydroxyphenyl)-1H-pyrroles. J Med Chem55:9607-18 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Estrogen receptor | |||
Name: | Estrogen receptor | ||
Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 | ||
Type: | Protein | ||
Mol. Mass.: | 66230.44 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P03372 | ||
Residue: | 595 | ||
Sequence: |
| ||
BDBM50398932 | |||
n/a | |||
Name | BDBM50398932 | ||
Synonyms: | CHEMBL2178797 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H22FNO3 | ||
Mol. Mass. | 403.4455 | ||
SMILES | CCCn1c(cc(c1-c1ccc(O)cc1F)-c1ccc(O)cc1)-c1ccc(O)cc1 |(37.4,-10.26,;37.07,-8.76,;38.21,-7.72,;37.89,-6.22,;36.48,-5.59,;36.63,-4.06,;38.14,-3.74,;38.91,-5.07,;40.44,-5.22,;41.33,-3.98,;42.86,-4.12,;43.5,-5.53,;45.03,-5.69,;42.6,-6.78,;41.07,-6.63,;40.17,-7.88,;38.76,-2.33,;40.29,-2.17,;40.91,-.76,;40,.5,;40.62,1.9,;38.46,.31,;37.85,-1.1,;35.14,-6.37,;33.8,-5.61,;32.48,-6.38,;32.47,-7.92,;31.14,-8.69,;33.81,-8.69,;35.14,-7.92,)| | ||
Structure |