| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50398948 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_875495 (CHEMBL2183136) |
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| Ki | 0.9±n/a nM |
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| Citation |  Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW Fumaroylamino-4,5-epoxymorphinans and related opioids with irreversibleµ opioid receptor antagonist effects. J Med Chem55:9868-74 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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| BDBM50398948 |
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| n/a |
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| Name | BDBM50398948 |
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| Synonyms: | CHEMBL2179261 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N2O6 |
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| Mol. Mass. | 508.6059 |
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| SMILES | COC(=O)\C=C\C(=O)NC[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O |r,THB:9:10:32.18:14.13| |
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| Structure | 
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