| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50399046 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_878773 (CHEMBL2183713) |
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| Ki | 38±n/a nM |
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| Citation |  Dahlgren, MK; Garcia, AB; Hare, AA; Tirado-Rives, J; Leng, L; Bucala, R; Jorgensen, WL Virtual screening and optimization yield low-nanomolar inhibitors of the tautomerase activity of Plasmodium falciparum macrophage migration inhibitory factor. J Med Chem55:10148-59 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | Macrophage migration inhibitory factor (MIF) |
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| Type: | Enzyme |
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| Mol. Mass.: | 12844.38 |
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| Organism: | Plasmodium falciparum |
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| Description: | Q6Q3H7 |
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| Residue: | 116 |
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| Sequence: | MPCCEVITNVNLPDDNVQSTLSQIENAISDVMGKPLGYIMSNYDYQKNLRFGGSNEAYCF
VRITSIGGINRSNNSALADQITKLLVSNLNVKSRRIYVEFRDCSAQNFAFSGSLFG
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| BDBM50399046 |
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| n/a |
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| Name | BDBM50399046 |
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| Synonyms: | CHEMBL2178862 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21NO3 |
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| Mol. Mass. | 335.3963 |
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| SMILES | COc1ccc(cc1)-c1cc(Oc2cc(C)cc(OC)c2)cc(C)n1 |
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| Structure | 
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