| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50399121 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_876706 (CHEMBL2183177) |
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| Ki | 22±n/a nM |
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| Citation |  Yang, P; Myint, KZ; Tong, Q; Feng, R; Cao, H; Almehizia, AA; Alqarni, MH; Wang, L; Bartlow, P; Gao, Y; Gertsch, J; Teramachi, J; Kurihara, N; Roodman, GD; Cheng, T; Xie, XQ Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. J Med Chem55:9973-87 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50399121 |
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| n/a |
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| Name | BDBM50399121 |
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| Synonyms: | CHEMBL2179751 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H35N3O2 |
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| Mol. Mass. | 457.6071 |
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| SMILES | CCCN(CCC)c1ccc(cc1)C(NC(=O)Cc1ccccc1)NC(=O)Cc1ccccc1 |
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| Structure | 
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