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TargetCannabinoid receptor 2
LigandBDBM50399122
Substrate/Competitorn/a
Meas. Tech.ChEMBL_876706 (CHEMBL2183177)
Ki 25±n/a nM
Citation Yang, PMyint, KZTong, QFeng, RCao, HAlmehizia, AAAlqarni, MHWang, LBartlow, PGao, YGertsch, JTeramachi, JKurihara, NRoodman, GDCheng, TXie, XQ Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. J Med Chem55:9973-87 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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BDBM50399122
n/a
NameBDBM50399122
Synonyms:CHEMBL2179734
TypeSmall organic molecule
Emp. Form.C23H39N3O2
Mol. Mass.389.5747
SMILESCCCCCC(=O)NC(NC(=O)CCCCC)c1ccc(cc1)N(CC)CC
Structure
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