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TargetP2X purinoceptor 4
LigandBDBM50399164
Substrate/Competitorn/a
Meas. Tech.ChEMBL_876875
IC50 2810±n/a nM
Citation Hernandez-Olmos VAbdelrahman AEl-Tayeb AFreudendahl DWeinhausen SMüller CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem 55:9576-88 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 4
Name:P2X purinoceptor 4
Synonyms:ATP receptor | P2X4 | P2rx4 | P2x4 | Purinergic receptor
Type:PROTEIN
Mol. Mass.:43443.55
Organism:Mus musculus
Description:ChEMBL_1283887
Residue:388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIP
DKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKRYYYRDKKYKYVEDYEQGLSGEMNQ
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  Blast E-value cutoff:
BDBM50399164
n/a
NameBDBM50399164
Synonyms:CHEMBL2180138
TypeSmall organic molecule
Emp. Form.C21H17NO3
Mol. Mass.331.3646
SMILESCc1ccc(COC(=O)N2c3ccccc3Oc3ccccc23)cc1
Structure
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