| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 4 |
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| Ligand | BDBM50118232 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_876876 (CHEMBL2184470) |
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| EC50 | 10000±n/a nM |
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| Citation |  Hernandez-Olmos, V; Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Weinhausen, S; Müller, CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem55:9576-88 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 4 |
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| Name: | P2X purinoceptor 4 |
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| Synonyms: | P2RX4_RAT | P2rx4 | Purinergic, P2X4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43504.16 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X4 0 RAT::P51577 |
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| Residue: | 388 |
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| Sequence: | MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIP
DKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKKYYYRDKKYKYVEDYEQGLSGEMNQ
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| BDBM50118232 |
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| n/a |
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| Name | BDBM50118232 |
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| Synonyms: | 2-MeSATP | ATP, 2-meS | CHEMBL336208 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H18N5O13P3S |
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| Mol. Mass. | 553.273 |
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| SMILES | CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 |
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| Structure | 
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