Ki Summary

Reaction Details

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Target

D(3) dopamine receptor

Ligand

BDBM50400515

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_879545 (CHEMBL2208954)

0.93±n/a nM

Citation

Chen, J; Collins, GT; Levant, B; Woods, J; Deschamps, JR; Wang, S CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist. ACS Med Chem Lett2:620-625 (2011) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

D(3) dopamine receptor

Name:

D(3) dopamine receptor

Synonyms:

DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3

Type:

Protein

Mol. Mass.:

49540.58

Organism:

Rattus norvegicus (Rat)

Description:

P19020

Residue:

446

Sequence:

MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC

BDBM50400515

n/a

Name

BDBM50400515

Synonyms:

CHEMBL2203402

Type

Small organic molecule

Emp. Form.

C29H38N4O2S

Mol. Mass.

506.703

SMILES

CCCN(CC[C@]1(O)CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1 |r,wU:6.5,10.13,wD:26.28,6.6,(11.35,-34.66,;11.36,-33.12,;10.02,-32.35,;10.03,-30.81,;11.36,-30.04,;12.69,-30.81,;14.03,-30.05,;14.02,-31.58,;15.36,-30.83,;16.69,-30.07,;16.7,-28.53,;15.37,-27.75,;14.02,-28.51,;18.04,-27.76,;19.37,-28.54,;19.36,-30.08,;20.73,-27.8,;20.73,-26.26,;22.05,-25.5,;23.37,-26.26,;24.7,-25.49,;26.04,-26.26,;26.03,-27.81,;24.7,-28.57,;23.37,-27.79,;22.06,-28.55,;8.69,-30.04,;8.69,-28.5,;7.36,-27.72,;6.04,-28.49,;4.56,-28.01,;3.65,-29.26,;2.11,-29.26,;4.56,-30.52,;6.04,-30.04,;7.36,-30.8,)|

Structure