Reaction Details | |||
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Target | D(3) dopamine receptor | ||
Ligand | BDBM50253393 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_879545 (CHEMBL2208954) | ||
Ki | 0.8±n/a nM | ||
Citation | Chen, J; Collins, GT; Levant, B; Woods, J; Deschamps, JR; Wang, S CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist. ACS Med Chem Lett2:620-625 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
D(3) dopamine receptor | |||
Name: | D(3) dopamine receptor | ||
Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 | ||
Type: | Protein | ||
Mol. Mass.: | 49540.58 | ||
Organism: | Rattus norvegicus (Rat) | ||
Description: | P19020 | ||
Residue: | 446 | ||
Sequence: |
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BDBM50253393 | |||
n/a | |||
Name | BDBM50253393 | ||
Synonyms: | CHEMBL495327 | Naphthalene-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-propyl-amino]-ethyl}-cyclohexyl)-amide | ||
Type | Small organic molecule | ||
Emp. Form. | C29H38N4OS | ||
Mol. Mass. | 490.703 | ||
SMILES | CCCN(CC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1 |r,wU:6.5,wD:25.27,9.12,(-.71,-29.3,;-.71,-27.76,;-2.04,-26.99,;-2.04,-25.45,;-.71,-24.68,;.63,-25.45,;1.96,-24.68,;1.95,-23.14,;3.3,-22.38,;4.63,-23.15,;4.62,-24.69,;3.29,-25.46,;5.96,-22.39,;7.29,-23.16,;7.29,-24.7,;8.63,-22.39,;9.96,-23.16,;11.29,-22.4,;11.29,-20.86,;12.62,-20.09,;12.62,-18.55,;11.28,-17.78,;9.95,-18.55,;9.95,-20.08,;8.62,-20.85,;-3.37,-24.67,;-3.37,-23.13,;-4.72,-22.35,;-6.05,-23.12,;-7.53,-22.64,;-8.45,-23.9,;-9.99,-23.9,;-7.53,-25.16,;-6.05,-24.67,;-4.72,-25.44,)| | ||
Structure |