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TargetRas-related protein Rap-1A
LigandBDBM50101929
Substrate/Competitorn/a
Meas. Tech.ChEMBL_879210 (CHEMBL2208523)
EC50>10000±n/a nM
Citation Marsault, EPeterson, ML Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery. J Med Chem54:1961-2004 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Ras-related protein Rap-1A
Name:Ras-related protein Rap-1A
Synonyms:C21KG | G-22K | GTP-binding protein smg p21A | KREV1 | RAP1A | RAP1A_HUMAN | Ras-related protein Krev-1
Type:PROTEIN
Mol. Mass.:20986.96
Organism:Homo sapiens (Human)
Description:ChEMBL_676192
Residue:184
Sequence:
MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
CLLL
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  Blast E-value cutoff:
BDBM50101929
n/a
NameBDBM50101929
Synonyms:3-oxo-18-oxa-2,5,9,11-tetraazahexacyclo[17.6.2.22,5.113,17.07,11.022,26]triaconta-1(26),7,9,13(30),14,16,19(27),20,22,24-decaen-16-yl cyanide | 3-oxo-18-oxa-2,5,9,11-tetraazahexacyclo[17.6.2.22,5.113,17.07,11.022,26]triaconta-1(26),7,9,13,15,17(30),19(27),20,22,24-decaen-16-yl cyanide | 4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile | CHEMBL52073
TypeSmall organic molecule
Emp. Form.C26H21N5O2
Mol. Mass.435.4772
SMILESO=C1CN2CCN1c1cccc3ccc(Oc4cc(Cn5cncc5C2)ccc4C#N)cc13
Structure
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