| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM50193921 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_879334 (CHEMBL2208732) |
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| Ki | 263±n/a nM |
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| Citation |  Meanwell, NA Synopsis of some recent tactical application of bioisosteres in drug design. J Med Chem54:2529-91 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 43335.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43115 |
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| Residue: | 390 |
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| Sequence: | MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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| BDBM50193921 |
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| n/a |
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| Name | BDBM50193921 |
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| Synonyms: | 3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamide | CHEMBL220802 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H19NO3S2 |
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| Mol. Mass. | 433.543 |
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| SMILES | O=C(NS(=O)(=O)c1cccs1)\C=C\c1ccccc1Cc1ccc2ccccc2c1 |
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| Structure | 
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