| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50400950 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_880272 (CHEMBL2215850) |
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| Ki | >316.23±n/a nM |
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| Citation |  Wijtmans, M; Verzijl, D; Bergmans, S; Lai, M; Bosch, L; Smit, MJ; de Esch, IJ; Leurs, R CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors. Bioorg Med Chem19:3384-93 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40665.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 368 |
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| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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| BDBM50400950 |
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| n/a |
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| Name | BDBM50400950 |
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| Synonyms: | CHEMBL2203305 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N |
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| Mol. Mass. | 343.5045 |
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| SMILES | CN(CC1=CC[C@H]2C[C@@H]1C2(C)C)Cc1ccc-2c(Cc3ccccc-23)c1 |r,t:3,TLB:2:3:7:9| |
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| Structure | 
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