| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50326219 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_882197 (CHEMBL2215470) |
|---|
| Ki | 891.25±n/a nM |
|---|
| Citation |  Daval, SB; Valant, C; Bonnet, D; Kellenberger, E; Hibert, M; Galzi, JL; Ilien, B Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors. J Med Chem55:2125-43 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51442.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11229 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50326219 |
|---|
| n/a |
|---|
| Name | BDBM50326219 |
|---|
| Synonyms: | 4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | CHEMBL1242950 | CHEMBL2206334 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H31NO |
|---|
| Mol. Mass. | 301.4662 |
|---|
| SMILES | CCCCC1CCN(CCCC(=O)c2ccccc2C)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
