| Reaction Details |
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 | Report a problem with these data |
| Target | Seed linoleate 13S-lipoxygenase-1 |
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| Ligand | BDBM50401193 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_881723 (CHEMBL2210181) |
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| Ki | 15700±n/a nM |
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| Citation |  Wisastra, R; Ghizzoni, M; Boltjes, A; Haisma, HJ; Dekker, FJ Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases. Bioorg Med Chem20:5027-32 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Seed linoleate 13S-lipoxygenase-1 |
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| Name: | Seed linoleate 13S-lipoxygenase-1 |
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| Synonyms: | 15-LOX | 15-Lipo-oxygenase (15-LO) | 15-lipo-oxygenase (SLO) | Arachidonic Acid 15- Lipoxygenase | L-1 | LOX1 | LOX1.1 | LOX1_SOYBN | Lipoxygenase (LOX) | Lipoxygenase (SLO) | Lipoxygenase-1 | Seed lipoxygenase-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 94365.66 |
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| Organism: | Glycine max (soybean) |
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| Description: | n/a |
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| Residue: | 839 |
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| Sequence: | MFSAGHKIKGTVVLMPKNELEVNPDGSAVDNLNAFLGRSVSLQLISATKADAHGKGKVGK
DTFLEGINTSLPTLGAGESAFNIHFEWDGSMGIPGAFYIKNYMQVEFFLKSLTLEAISNQ
GTIRFVCNSWVYNTKLYKSVRIFFANHTYVPSETPAPLVSYREEELKSLRGNGTGERKEY
DRIYDYDVYNDLGNPDKSEKLARPVLGGSSTFPYPRRGRTGRGPTVTDPNTEKQGEVFYV
PRDENLGHLKSKDALEIGTKSLSQIVQPAFESAFDLKSTPIEFHSFQDVHDLYEGGIKLP
RDVISTIIPLPVIKELYRTDGQHILKFPQPHVVQVSQSAWMTDEEFAREMIAGVNPCVIR
GLEEFPPKSNLDPAIYGDQSSKITADSLDLDGYTMDEALGSRRLFMLDYHDIFMPYVRQI
NQLNSAKTYATRTILFLREDGTLKPVAIELSLPHSAGDLSAAVSQVVLPAKEGVESTIWL
LAKAYVIVNDSCYHQLMSHWLNTHAAMEPFVIATHRHLSVLHPIYKLLTPHYRNNMNINA
LARQSLINANGIIETTFLPSKYSVEMSSAVYKNWVFTDQALPADLIKRGVAIKDPSTPHG
VRLLIEDYPYAADGLEIWAAIKTWVQEYVPLYYARDDDVKNDSELQHWWKEAVEKGHGDL
KDKPWWPKLQTLEDLVEVCLIIIWIASALHAAVNFGQYPYGGLIMNRPTASRRLLPEKGT
PEYEEMINNHEKAYLRTITSKLPTLISLSVIEILSTHASDEVYLGQRDNPHWTSDSKALQ
AFQKFGNKLKEIEEKLVRRNNDPSLQGNRLGPVQLPYTLLYPSSEEGLTFRGIPNSISI
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| BDBM50401193 |
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| n/a |
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| Name | BDBM50401193 |
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| Synonyms: | CHEMBL1934604 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28O4 |
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| Mol. Mass. | 356.4553 |
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| SMILES | CCCCCCCc1ccc(CCc2cc(O)cc(O)c2C(O)=O)cc1 |
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| Structure | 
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