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TargetC-C chemokine receptor type 5
LigandBDBM64740
Substrate/Competitorn/a
Meas. Tech.ChEMBL_884038
EC50 63095.73±n/a nM
Citation Thiele SMalmgaard-Clausen MEngel-Andreasen JSteen ARummel PCNielsen MCGloriam DEFrimurer TMUlven TRosenkilde MM Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. J Med Chem 55:8164-77 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-C chemokine receptor type 5
Name:CCR5/mu opioid receptor complex
Synonyms:C-C CKR-5 | CC-CKR-5 | CCR-5 | CCR5/mu opioid receptor complex | CD_antigen=CD195 | CHEMR13 | HIV-1 fusion coreceptor
Type:Enzyme
Mol. Mass.:40540.21
Organism:Homo sapiens (Human)
Description:P51681
Residue:352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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  Blast E-value cutoff:
BDBM64740
n/a
NameBDBM64740
Synonyms:2,9-dimethyl-1,10-phenanthroline | MLS001194484 | SMR000555011 | cid_65237
TypeSmall organic molecule
Emp. Form.C14H12N2
Mol. Mass.208.2585
SMILESCc1ccc2ccc3ccc(C)nc3c2n1
Structure
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