| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 8 |
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| Ligand | BDBM50401340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_884037 (CHEMBL2215086) |
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| EC50 | >1000000±n/a nM |
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| Citation |  Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. J Med Chem55:8164-77 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 8 |
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| Name: | C-C chemokine receptor type 8 |
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| Synonyms: | CCR8 | CCR8_HUMAN | CKRL1 | CMKBR8 | CMKBRL2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40855.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_454278 |
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| Residue: | 355 |
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| Sequence: | MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
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| BDBM50401340 |
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| n/a |
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| Name | BDBM50401340 |
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| Synonyms: | CHEMBL1976682 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10Br2N2 |
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| Mol. Mass. | 366.051 |
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| SMILES | BrCc1ccc2ccc3ccc(CBr)nc3c2n1 |
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| Structure | 
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