| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 5 |
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| Ligand | BDBM50042874 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_884030 (CHEMBL2215079) |
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| IC50 | 79432.82±n/a nM |
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| Citation |  Thiele, S; Malmgaard-Clausen, M; Engel-Andreasen, J; Steen, A; Rummel, PC; Nielsen, MC; Gloriam, DE; Frimurer, TM; Ulven, T; Rosenkilde, MM Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. J Med Chem55:8164-77 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 5 |
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| Name: | C-C chemokine receptor type 5 |
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| Synonyms: | C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40540.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51681 |
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| Residue: | 352 |
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| Sequence: | MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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| BDBM50042874 |
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| n/a |
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| Name | BDBM50042874 |
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| Synonyms: | 2,2'-Bipyridin | 2,2'-bipyridine | 2,2'-bipyridyl | 2,2'-dipyridine | 2,2'-dipyridyl | 2-(2-pyridyl)pyridine | CHEMBL39879 | US10196346, Bipyridine | alpha,alpha'-bipyridine | alpha,alpha'-bipyridyl | alpha,alpha'-dipyridine | alpha,alpha'-dipyridyl | bpy |
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| Type | Small organic molecule |
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| Emp. Form. | C10H8N2 |
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| Mol. Mass. | 156.1839 |
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| SMILES | c1ccc(nc1)-c1ccccn1 |
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| Structure | 
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