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TargetC-C chemokine receptor type 8
LigandBDBM38924
Substrate/Competitorn/a
Meas. Tech.ChEMBL_884037
EC50 5011.87±n/a nM
Citation Thiele SMalmgaard-Clausen MEngel-Andreasen JSteen ARummel PCNielsen MCGloriam DEFrimurer TMUlven TRosenkilde MM Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. J Med Chem 55:8164-77 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-C chemokine receptor type 8
Name:C-C chemokine receptor type 8
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:40855.53
Organism:Homo sapiens (Human)
Description:ChEMBL_454278
Residue:355
Sequence:
MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVL
VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSS
MFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGV
LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLV
LIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIY
AFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
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  Blast E-value cutoff:
BDBM38924
n/a
NameBDBM38924
Synonyms:2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)pyridine | 2,6-dipyridin-2-ylpyridine | MLS000048666 | SMR000060049 | cid_70848
TypeSmall organic molecule
Emp. Form.C15H11N3
Mol. Mass.233.2679
SMILESc1ccc(nc1)-c1cccc(n1)-c1ccccn1
Structure
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