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TargetIndoleamine 2,3-dioxygenase 2
LigandBDBM50402289
Substrate/Competitorn/a
Meas. Tech.ChEMBL_885588
IC50 1800±n/a nM
Citation Bakmiwewa SMFatokun AATran APayne RJHunt NHBall HJ Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorg Med Chem Lett 22:7641-6 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Indoleamine 2,3-dioxygenase 2
Name:Indoleamine 2,3-dioxygenase 2
Synonyms:IDO-2 | Ido2 | Indol1 | Indoleamine 2,3-dioxygenase-like protein 1 | Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
Type:PROTEIN
Mol. Mass.:45256.34
Organism:Mus musculus
Description:ChEMBL_105489
Residue:405
Sequence:
MEPQSQSMTLEVPLSLGRYHISEEYGFLLPNPLEALPDHYKPWMEIALRLPHLIENRQLR
AHVYRMPLLDCRFLKSYREQRLAHMALAAITMGFVWQEGEGQPQKVLPRSLAIPFVEVSR
NLGLPPILVHSDLVLTNWTKRNPEGPLEISNLETIISFPGGESLRGFILVTVLVEKAAVP
GLKALVQGMEAIRQHSQDTLLEALQQLRLSIQDITRALAQMHDYVDPDIFYSVIRIFLSG
WKDNPAMPVGLVYEGVATEPLKYSGGSAAQSSVLHAFDEFLGIEHCKESVGFLHRMRDYM
PPSHKAFLEDLHVAPSLRDYILASGPGDCLMAYNQCVEALGELRSYHINVVARYIISAAT
RARSRGLTNPSPHALEDRGTGGTAMLSFLKSVREKTMEALLCPGA
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  Blast E-value cutoff:
BDBM50402289
n/a
NameBDBM50402289
Synonyms:TENATOPRAZOLE
TypeSmall organic molecule
Emp. Form.C16H18N4O3S
Mol. Mass.346.404
SMILESCOc1ccc2[nH]c(nc2n1)S(=O)Cc1ncc(C)c(OC)c1C
Structure
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